Coach Kyle Shanahan said Guerendo (foot/hamstring) will be limited at Thursday's practice, Cam Inman of The San Jose Mercury News reports. As Shanahan projected Monday, Guerendo is returning to the practice field for the first time since Week 15 prep, which is a good sign after he sat out Week 16 in Miami due to foot and hamstring injuries. If Guerendo is able to make it through the week unscathed and suit up Monday against the Lions, he'd provide a boost for a 49ers backfield that will be without Christian McCaffrey (knee) and Jordan Mason (ankle) in Week 17.

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Status
QUESTIONABLE - Hamstring - Not Specified Expected Return: 2024-12-30Previous game (vs. LA 12/12)
Latest Isaac Guerendo news
2024 Season Rushing
2024 Season Receiving

Isaac Guerendo Career Stats
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Career Stats - Rushing
CARYDSAVGTDLNGFDFUM733815.2476153Career Stats - Receiving
RECTGTSYDSAVGTDLNGYAC1112877.90276Rushing
Season Team CAR YDS AVG TD LNG FD FUM 2024 SF 73 381 5.2 4 76 15 3 Career 733815.2476153Receiving
Season Team REC TGTS YDS AVG TD LNG YAC 2024 SF 11 12 87 7.9 0 27 6.2 Career 1112877.90276

Isaac Guerendo Season Stats 2024
Previous Game (vs. LA 12/12)
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Rushing
CARYDSAVGTDLNGFDFUM733815.2476153Receiving
RECTGTSYDSAVGTDLNGYAC1112877.90276.2

Isaac Guerendo Game Log 2024
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PreseasonrushingreceivingDateOppResultCARYDSAVGTDLNGFDRECTGTSYDSAVGTDSLNGYAC8/23T 24-2411322.90622231.5022
Preseason Totals 11322.90622231.5022 -
Regular SeasonrushingreceivingDateOppResultCARYDSAVGTDLNGFDRECTGTSYDSAVGTDSLNGYAC12/12L 6-1216573.6016344184.50102112/8W 38-1315785.223032250250272412/1L 10-354194.8115111-3-30-3211/10W 23-20100000-------10/27W 30-2414856.1119434175.70121610/20L 18-28122020115505410/10W 36-2410999.90763-------10/6L 23-245224.4051-------9/29W 30-13100000-------9/22L 24-275193.8060-------9/15L 17-23100000-------
Regular Season Totals 733813.6476151112877.402767

Isaac Guerendo Player Profile
Career History


Isaac Guerendo Latest News
To be limited Thursday

Coach Kyle Shanahan said Guerendo (foot/hamstring) will be limited at Thursday's practice, Cam Inman of The San Jose Mercury News reports. As Shanahan projected Monday, Guerendo is returning to the practice field for the first time since Week 15 prep, which is a good sign after he sat out Week 16 in Miami due to foot and hamstring injuries. If Guerendo is able to make it through the week unscathed and suit up Monday against the Lions, he'd provide a boost for a 49ers backfield that will be without Christian McCaffrey (knee) and Jordan Mason (ankle) in Week 17.
Likely to practice Thursday

Coach Kyle Shanahan said Monday that the 49ers expect Guerendo (foot/hamstring) to practice Thursday, Nick Wagoner of ESPN.com reports. Guerendo emerged from a Week 15 loss to the Rams with foot and hamstring injuries that ultimately kept him off the practice field last week and out for Sunday's defeat at Miami. In Guerendo's place Week 16, Patrick Taylor got the start at running back and played 51 of 64 offensive snaps, but he mustered just 25 yards from scrimmage on nine touches. Meanwhile, Deebo Samuel moonlighted with five carries for 25 yards, and fullback Kyle Juszczyk also had two touches for 26 total yards. Guerendo's return to the field Thursday will be accompanied with a corresponding listing on the injury report, so a limited or even full showing will be an encouraging sign for the 49ers backfield.
Ruled out for Week 16

Guerendo (foot/hamstring) has been ruled out for Sunday's game at Miami, Matt Maiocco of NBC Sports Bay Area reports. Guerendo didn't practice this week and thus appears in danger of missing time beyond Sunday. His absence leaves Patrick Taylor and Israel Abanikanda atop the depth chart at running back, with Ke'Shawn Vaughn likely to be elevated from the practice squad before Sunday. Taylor filled in as the lead back when Guerendo missed a chunk of San Francisco's Week 14 game with a foot injury, but that doesn't necessarily mean Taylor will dominate carries Sunday afternoon with more time to prepare for Guerendo's absence.
Trending in wrong direction

The 49ers are not expected to have Guerendo (hamstring) available for Sunday's game against the Dolphins, Adam Schefter of ESPN reports. Guerendo missed Wednesday's practice session due to a new hamstring injury, and Schefter's reporting makes it seem as though he'll be officially listed as a non-participant again Thursday. The rookie fourth-round pick managed to play through a foot sprain during last Thursday's 12-6 loss to the Rams, in which he rushed 16 times for 57 yards and brought in all four targets for 18 yards, handling all of San Francisco's running back touches. Head coach Kyle Shanahan hasn't yet commented on Guerendo's status for Week 16, but if he's indeed sidelined on the road against Miami, Patrick Taylor, Israel Abanikanda and practice-squad player Ke'Shawn Vaughn will be next up for backfield reps.
Sidelined with hamstring injury

Guerendo will not practice Wednesday due to foot and hamstring injuries, David Lombardi of SFStandard.com reports. Guerendo played through a foot sprain in last Thursday's 12-6 loss to the Rams, and though he didn't experience any reported in-game setbacks with that injury, he's emerged from the contest with a new health concern. With Christian McCaffrey (knee) and Jordan Mason (ankle) both on injured reserve, the 49ers could realistically be taking a cautious approach to Guerendo's health, but his activity will now need to be monitored during practices Thursday and Friday. Patrick Taylor, Israel Abanikanda and practice-squad member Ke'Shawn Vaughn, are San Francisco's available backfield options behind Guerendo heading into a road matchup against the Dolphins on Sunday.
Garners 75 total yards in loss

Guerendo rushed 16 times for 57 yards and brought in all four targets for 18 yards in the 49ers' 12-6 loss to the Rams on Thursday night. Guerendo overcame the foot sprain he'd suffered in the Week 14 win over the Bears on Sunday to suit up and handle all of San Francisco's running back touches. However, the rookie surprisingly found some tough sledding against a Rams defense that has been beatable on the ground at times this season. Nevertheless, Guerendo impressively handled a solid workload in wet conditions and finished as the co-leader in receptions as well, and he'll have a secure fantasy floor as the clear lead back when the 49ers travel to face the Dolphins on Sunday, Dec. 22.
Active in Week 15

Guerendo (foot) is listed as active Thursday against the Rams, Lindsey Pallares of the 49ers' official site reports. Guerendo came out of this past Sunday's win versus the Bears with a sprained foot, which left his status for Week 15 up in the air. He wasn't able to practice until Wednesday, when he was listed as limited, and both Adam Schefter of ESPN and Matt Barrows of The Athletic reported at different points Thursday that Guerendo felt good following that session and intended to play. Indeed, that has come to pass, but it remains to be seen if Guerendo will handle the majority of backfield reps for the 49ers. Patrick Taylor and Ke'Shawn Vaughn also are on hand for work at running back.
Planning to play through sprained foot

Guerendo (foot) remains listed as questionable for Thursday's game against the Rams but insists he "feels good" and plans to play, sources tell Adam Schefter of ESPN. After Christian McCaffrey (knee) and Jordan Mason (ankle) were moved to injured reserve last week, Guerendo stepped in as the 49ers' starting running back in this past Sunday's 38-13 win over the Bears. He turned in a big performance, rushing 15 times for 78 yards and two scores while chipping in two catches for 50 yards before exiting late in the contest with a sprained foot. The 49ers listed Guerendo as a non-participant on injury reports released Monday and Tuesday, but after upgrading to limited activity in Wednesday's walk-through session, the rookie looks like he could be tracking toward playing against the Rams. Official word on Guerendo's status will come when the 49ers release their inactive list 90 minutes before Thursday's 8:15 p.m. ET kickoff, but even if he's cleared to play, the 49ers could aim to limit his workload on a short week. Patrick Taylor and Israel Abanikanda are already on the roster as backup options behind Guerendo, and the 49ers could also elevate Ke'Shawn Vaughn from the practice squad to provide another healthy body out of the backfield.
Status in question for Thursday

Guerendo (foot) is listed as questionable for Thursday's game versus the Rams, Eric Branch of the San Francisco Chronicle reports. Despite operating on a short week between games, the 49ers are keeping the door open for Guerendo to suit up Week 15 following the foot sprain that forced him out of the fourth quarter of this past Sunday's win against the Bears. He was a listed DNP on both Monday and Tuesday. If he's unable to go Thursday, Guerendo will hand off San Fransisco's backfield to Patrick Taylor, with Israel Abanikanda and practice-squad member Ke'Shawn Vaughn available behind him.